This includes all neurodegenerative disorders except Alzheimer’s Disease which has been given a separate section.

• Leveraging Human Cell Atlas technologies to shed light on the immune aetiology of chronic inflammatory demyelinating polyradiculoneuropathy
  Brain UK study ref: 24/005, Lay summary, Project status: Active… Read more: Leveraging Human Cell Atlas technologies to shed light on the immune aetiology of chronic inflammatory demyelinating polyradiculoneuropathy
• Genome and transcriptome analysis in DRPLA, other rare repeat expansion disorders and undiagnosed inherited ataxia tissue
  Brain UK study ref: 23/026, Lay summary, Project status: Active… Read more: Genome and transcriptome analysis in DRPLA, other rare repeat expansion disorders and undiagnosed inherited ataxia tissue
• SPCA in ALS
  Brain UK study ref: 23/009, Lay summary, Project status: Active… Read more: SPCA in ALS
• Studying the pathogenesis of Huntington’s disease in post-mortem tissues
  Brain UK study ref: 23/004, Lay summary, Project status: Active… Read more: Studying the pathogenesis of Huntington’s disease in post-mortem tissues
• TDP-43 pathology and loss of function in the skeletal muscle
  Brain UK study ref: 22/006, Lay summary, Project status: Active… Read more: TDP-43 pathology and loss of function in the skeletal muscle
• Single-cell transcriptomics of prion diseases
  Brain UK study ref: 22/005, Lay summary, Project status: Closed… Read more: Single-cell transcriptomics of prion diseases
• Ultrastructural Endoneurial Pathology to Explain the Normal Function of the Human Blood Nerve Barrier and the Pathogenesis of Inflammatory Nerve Disease
  Brain UK study ref: 20/004, Lay summary, Project status: Closed… Read more: Ultrastructural Endoneurial Pathology to Explain the Normal Function of the Human Blood Nerve Barrier and the Pathogenesis of Inflammatory Nerve Disease
• C1q in Huntington’s disease
  Brain UK study ref: 19/008, Lay summary, Project status: Closed… Read more: C1q in Huntington’s disease
• Pathological and genetic study of an unusual case of alpha-synucleinopathy
  Brain UK study ref: 19/007, Lay summary, Project status: Active… Read more: Pathological and genetic study of an unusual case of alpha-synucleinopathy
• The Dynamics of Microglia in the Human Brain
  Brain UK study ref: 17/014, Lay summary, Project status: Active… Read more: The Dynamics of Microglia in the Human Brain
• Tau and A2AR expression in Alexander’s disease
  Brain UK study ref: 17/011, Lay summary, Project status: Active… Read more: Tau and A2AR expression in Alexander’s disease
• Pathological study of two cases with SLC52A3 mutation
  Brain UK study ref: 17/001, Lay summary, Project status: Closed… Read more: Pathological study of two cases with SLC52A3 mutation
• Selective vulnerability in MND/FTD
  Brain UK study ref: 16/010, Lay summary, Project status: Closed… Read more: Selective vulnerability in MND/FTD
• Consensus diagnostic criteria of a novel tauopathy associated with anti-IgLON5
  Brain UK study ref: 16/005, Lay summary, Project status: Closed… Read more: Consensus diagnostic criteria of a novel tauopathy associated with anti-IgLON5
• Studying the turnover of oligodendrocytes in Huntington’s disease
  Brain UK study ref: 15/020, Lay summary, Project status: Active… Read more: Studying the turnover of oligodendrocytes in Huntington’s disease
• Pilot study: Expression of Bim in Huntington’s Disease
  Brain UK study ref: 14/007, Lay summary, Project status: Active… Read more: Pilot study: Expression of Bim in Huntington’s Disease
• Are neurodegenerative diseases and gliomas inverse comorbidities?
  Brain UK study ref: 13/001, Lay summary, Project status: Closed… Read more: Are neurodegenerative diseases and gliomas inverse comorbidities?
• The impact of mitochondrial DNA mutations on substantia nigra neurons
  Brain UK study ref: 12/006, Lay summary, Project status: Closed… Read more: The impact of mitochondrial DNA mutations on substantia nigra neurons
• Evidence for stem cell neuroprotection in genetic ataxias
  Brain UK study ref: 12/004, Lay summary, Project status: Active… Read more: Evidence for stem cell neuroprotection in genetic ataxias
• Comparative study of the neuropathology in Huntington’s disease brains
  Brain UK study ref: 11/006, Lay summary, Project status: Closed… Read more: Comparative study of the neuropathology in Huntington’s disease brains