Glioblastoma is the most frequent brain tumour in adult. Despite the current treatment, the diagnosis of brain tumour is associated with with a short survival time of around 1 year. Brain tumour is composed of a mix of inflammatory and tumour cells. The current thinking is that the inflammatory cells are participating in the growth of the tumour instead of recognising the tumour cells as a pathogen. With this project,we wish to characterise the inflammatory cells and their relationship with the tumour cells. The information collected will be used to develop a laboratory model similar to the human brain tumour allowing manipulation of the inflammatory cells or the tumour cells to identify a target for treatment.