Brain UK study ref: 25/004,

Lay summary,

Project status: Active

Fibre Types and Structural Patterns in Skeletal Muscle
Development and Pathology

Dr Karl Frontzek, University College London

Our muscles help us move and perform daily activities thanks to a complex process involving specific proteins, one of which is called MyHC-2X. This protein is crucial for muscle development and function, but there’s still a lot we don’t know about how it varies among different people and health conditions.
Our research team has created a new method to identify MyHC-2X and similar proteins in muscle tissues. In our early studies, we discovered that MyHC-2X becomes more common as we age. However, many questions remain unanswered. By studying how MyHC-2X behaves in people of different ages, genders, locations, and health conditions, we aim to learn more about muscle health and diseases.
This research is not just about understanding muscles better; it’s also about developing new treatments. By learning more about proteins like MyHC-2X, we hope to create innovative therapies for muscle-related disorders and injuries, offering hope for those affected by these conditions.